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Simple analysis method for dioxins using  bioassay technology

Technology / Service Summary

CALUX is a bioassay method for dioxins using the nationally and internationally recognized reporter gene assay method.


Simple and rapid measurement of dioxins
in the environment, products, and living organisms.


・Unlike conventional methods (HRGC/HRMS), expensive equipment and complicated operations are not required.
• It is a simple, rapid, low-cost analytical method.
・It is effective for simultaneous analysis of a large amount of samples.


"∙ Measurements can be made at less than 1/2 the price and 1/3 the speed of conventional methods.
・Cooperation and support on training, medium- and country-specific validation."

Controlled Substance

  • Dioxin


Applicable Regions / Countries

  • Japan
  • Southeast Asia
  • Central/South Asia
  • China/ East Asia
  • Europe
  • Central/South America
  • ASEAN countries

    Indonesia,Cambodia,Singapore,Thailand,Philippines,Brunei Darussalam,Viet Nam,Malaysia,Myanmar,Lao PDR


"Japan: Adopted for exhaust gas, soot and cinders in Ministry of the Environment Notification No. 92, September 2005.
Adopted in US EPA Method 4435 (analysis of sludge).
EU EC Directive of July 26, 2002 Adopted for screening tests for food and feed.
Taiwan: Adopted for investigation of soils by the Ministry of the Environment, Taiwan.
Vietnam Adopted for a feasibility study to promote environmental monitoring of dioxins using a simple analytical method (JICA SME support type).
Lao PDR Adopted for the World Bank POPs bio-monitoring project (defoliants, soil at waste collection points, fish, breast milk)
China Joint laboratory established with China National Centre for Environmental Analysis (Beijing).
Other universities and public and private laboratories in Belgium, Poland, Chile, China and Taiwan have introduced the system."

Locations for inspection

Hiyoshi Corporation
(908, Kitanosho, Omihachiman, Shiga, Japan).

Related SDGs Goals

  • 3. Good Health and Well-being
  • 6. Clean Water and Sanitation

Simple analysis method for dioxins using  bioassay technology